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Synergistic cytotoxicity of homoharringtonine and etoposide in acute myeloid leukemia cells involves disrupted antioxidant defense

BACKGROUND/AIMS: Cytotoxicity induced by reactive oxygen species (ROS) is critical for the effectiveness of chemotherapeutic drugs used in the treatment of acute myeloid leukemia (AML). This study aimed to investigate whether ROS contributes to cytotoxicity in AML cells when treated with homoharring...

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Detalles Bibliográficos
Autores principales:	Zhang, Jingjing, Geng, Huayun, Liu, Ling, Zhang, Hao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2019
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6349074/ https://www.ncbi.nlm.nih.gov/pubmed/30774430 http://dx.doi.org/10.2147/CMAR.S187597

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