Cargando…

Up‐regulation of SPINT2/HAI‐2 by Azacytidine in bone marrow mesenchymal stromal cells affects leukemic stem cell survival and adhesion

The role of tumour microenvironment in neoplasm initiation and malignant evolution has been increasingly recognized. However, the bone marrow mesenchymal stromal cell (BMMSC) contribution to disease progression remains poorly explored. We previously reported that the expression of serine protease in...

Descripción completa

Detalles Bibliográficos
Autores principales:	Roversi, Fernanda Marconi, Cury, Nathalia Moreno, Lopes, Matheus Rodrigues, Ferro, Karla Priscila, Machado‐Neto, João Agostinho, Alvarez, Marisa Claudia, dos Santos, Gabriela Pereira, Giardini Rosa, Renata, Longhini, Ana Leda, Duarte, Adriana da Silva Santos, Pericole, Fernando Vieira, Favaro, Patricia, Yunes, José Andres, Saad, Sara Teresinha Olalla
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2018
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6349149/ https://www.ncbi.nlm.nih.gov/pubmed/30484958 http://dx.doi.org/10.1111/jcmm.14066

Ejemplares similares

Hematopoietic Cell Kinase (HCK) Is a Player of the Crosstalk Between Hematopoietic Cells and Bone Marrow Niche Through CXCL12/CXCR4 Axis
por: Roversi, Fernanda Marconi, et al.
Publicado: (2021)

BRD4 Inhibition Enhances Azacitidine Efficacy in Acute Myeloid Leukemia and Myelodysplastic Syndromes
por: Pericole, Fernando Vieira, et al.
Publicado: (2019)

CXCR7 participates in CXCL12-mediated migration and homing of leukemic and normal hematopoietic cells
por: Melo, Rita de Cassia Carvalho, et al.
Publicado: (2018)

STYK1 promotes tumor growth and metastasis by reducing SPINT2/HAI-2 expression in non-small cell lung cancer
por: Ma, Zhiqiang, et al.
Publicado: (2019)

Hepatocyte growth factor activator inhibitor type-2 (HAI-2)/SPINT2 contributes to invasive growth of oral squamous cell carcinoma cells
por: Yamamoto, Koji, et al.
Publicado: (2018)

Stathmin 1 expression in plasma cell neoplasms
por: Machado-Neto, João Agostinho, et al.
Publicado: (2017)

Artesunate Switches Monocytes to an Inflammatory Phenotype with the Ability to Kill Leukemic Cells
por: Mancuso, Rubia Isler, et al.
Publicado: (2021)

Decreased expression of SPINT1-AS1 and SPINT1 mRNA might be independent unfavorable prognostic indicators in esophageal squamous cell carcinoma
por: Shen, Fang-Fang, et al.
Publicado: (2019)

Immunomodulatory Effect of Green Tea Treatment in Combination with Low-dose Chemotherapy in Elderly Acute Myeloid Leukemia Patients with Myelodysplasia-related Changes
por: Calgarotto, Andrana K., et al.
Publicado: (2021)

Elevated Circulating and Placental SPINT2 Is Associated with Placental Dysfunction
por: Murphy, Ciara N., et al.
Publicado: (2021)

CXCR7 Is Highly Expressed in Acute Lymphoblastic Leukemia and Potentiates CXCR4 Response to CXCL12
por: Melo, Rita de Cássia Carvalho, et al.
Publicado: (2014)

Differential profile of CDKN1A and TP53 expressions in bone marrow mesenchymal stromal cells from myeloid neoplasms
por: Lopes, Matheus Rodrigues, et al.
Publicado: (2016)

Aberrant methylation and silencing of the SPINT2 gene in high‐grade gliomas
por: Fukushima, Tsuyoshi, et al.
Publicado: (2018)

Arhgap21 Deficiency Results in Increase of Osteoblastic Lineage Cells in the Murine Bone Marrow Microenvironment
por: Pissarra, Mariana Ferreira, et al.
Publicado: (2021)

SPINT2 inhibits proteases involved in activation of both influenza viruses and metapneumoviruses
por: Straus, Marco R., et al.
Publicado: (2020)

Comprehensive Analysis of the Expression and Prognostic Value of SPINT1/2 in Breast Carcinoma
por: Wu, Qiulin, et al.
Publicado: (2021)

Novel Non-Coding Transcript in NR4A3 Locus, LncNR4A3, Regulates RNA Processing Machinery Proteins and NR4A3 Expression
por: Congrains, Ada, et al.
Publicado: (2020)

Development of an Oral Form of Azacytidine: 2′3′5′Triacetyl-5-Azacytidine
por: Ziemba, Amy, et al.
Publicado: (2011)

Obesity as a Possible Risk Factor for Progression from Monoclonal Gammopathy of Undetermined Significance Progression into Multiple Myeloma: Could Myeloma Be Prevented with Metformin Treatment?
por: da Cunha Júnior, Ademar Dantas, et al.
Publicado: (2021)

Circulating SPINT1 is a biomarker of pregnancies with poor placental function and fetal growth restriction
por: Kaitu’u-Lino, Tu’uhevaha J., et al.
Publicado: (2020)

Circulating SPINT1 Is Reduced in a Preeclamptic Cohort with Co-Existing Fetal Growth Restriction
por: Murphy, Ciara N., et al.
Publicado: (2022)

Azacytidine Treatment for VEXAS Syndrome
por: Raaijmakers, Marc H. G. P., et al.
Publicado: (2021)

Neuroprotection and immunomodulation by xenografted human mesenchymal stem cells following spinal cord ventral root avulsion
por: Ribeiro, Thiago B., et al.
Publicado: (2015)

Matriptase Complexes and Prostasin Complexes with HAI-1 and HAI-2 in Human Milk: Significant Proteolysis in Lactation
por: Lai, Chih-Hsin, et al.
Publicado: (2016)

Incidence of Healthcare-Associated Infections (HAIs) and the adherence to the HAIs’ prevention strategies in a military hospital in Alkharj
por: Ahmed, Nehad J., et al.
Publicado: (2021)

LncRNAs GIHCG and SPINT1-AS1 Are Crucial Factors for Pan-Cancer Cells Sensitivity to Lapatinib
por: Xiang, Zhen, et al.
Publicado: (2019)

SPINT1-AS1 Drives Cervical Cancer Progression via Repressing miR-214 Biogenesis
por: Song, Hongjuan, et al.
Publicado: (2021)

Health Care–Associated Infections (HAIs)
por: Almeida, Sherri-Lynne
Publicado: (2015)

Azacytidine (Vidaza®) in the treatment of myelodysplastic syndromes
por: Raj, Kavita, et al.
Publicado: (2006)

Teriflunomide restores 5-azacytidine sensitivity via activation of pyrimidine salvage in 5-azacytidine-resistant leukemia cells
por: Imanishi, Satoshi, et al.
Publicado: (2017)

Functional Analysis of a Missense Mutation in the Serine Protease Inhibitor SPINT2 Associated with Congenital Sodium Diarrhea
por: Faller, Nicolas, et al.
Publicado: (2014)

Epigenetic Silencing of SPINT2 promotes Cancer Cell Motility via HGF-MET Pathway Activation in Melanoma
por: Hwang, Soonyean, et al.
Publicado: (2015)

Loss of USP28 and SPINT2 expression promotes cancer cell survival after whole genome doubling
por: Bernhard, Sara Vanessa, et al.
Publicado: (2021)

Stathmin 1 in normal and malignant hematopoiesis
por: Machado-Neto, João Agostinho, et al.
Publicado: (2014)

The Expression and Activation of the NF-κB Pathway Correlate with Methotrexate Resistance and Cell Proliferation in Acute Lymphoblastic Leukemia
por: Canevarolo, Rafael Renatino, et al.
Publicado: (2023)

Zebrafish modeling reveals that SPINT1 regulates the aggressiveness of skin cutaneous melanoma and its crosstalk with tumor immune microenvironment
por: Gómez-Abenza, Elena, et al.
Publicado: (2019)

Exosome‐delivered miR‐221/222 exacerbates tumor liver metastasis by targeting SPINT1 in colorectal cancer
por: Tian, Fei, et al.
Publicado: (2021)

Stathmin 1 inhibition amplifies ruxolitinib-induced apoptosis in JAK2(V617F) cells
por: Machado-Neto, João Agostinho, et al.
Publicado: (2015)

Tissue distribution and subcellular localizations determine in vivo functional relationship among prostasin, matriptase, HAI-1, and HAI-2 in human skin
por: Lee, Shiao-Pieng, et al.
Publicado: (2018)

Decellularized Dental Pulp, Extracellular Vesicles, and 5-Azacytidine: A New Tool for Endodontic Regeneration
por: Diomede, Francesca, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_gsg4ck8bo101sjag3lmfafa4r3