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Effect of atorvastatin on cardiomyocyte hypertrophy through suppressing MURC induced by volume overload and cyclic stretch

MURC (muscle‐restricted coiled‐coil protein) is a hypertrophy‐related gene. Hypertrophy can be induced by mechanical stress. The purpose of this research was to investigate the hypothesis that MURC mediates hypertrophy in cardiomyocytes under mechanical stress. We used the in vivo model of an aortoc...

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Detalles Bibliográficos
Autores principales: Cheng, Wen‐Pin, Lo, Huey‐Ming, Wang, Bao‐Wei, Chua, Su‐Kiat, Shyu, Kou‐Gi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6349245/
https://www.ncbi.nlm.nih.gov/pubmed/30511410
http://dx.doi.org/10.1111/jcmm.14044