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Prenatal hypoxia plus postnatal high‐fat diet exacerbated vascular dysfunction via up‐regulated vascular Cav1.2 channels in offspring rats
BACKGROUND: This study aimed to examine whether and how postnatal high‐fat diet had additional impact on promoting vascular dysfunction in the offspring exposed to prenatal hypoxia. METHODS AND RESULTS: Pregnant Sprague‐Dawley rats were randomly assigned to hypoxia (10.5% oxygen) or normoxia (21% O(...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6349350/ https://www.ncbi.nlm.nih.gov/pubmed/30556291 http://dx.doi.org/10.1111/jcmm.14020 |