High-Throughput Assessment of Structural Continuity in Biologics

[Image: see text] We demonstrate a high-throughput chemoprinting platform that confirms the consistency in the higher-order structure of protein biologics and is sensitive enough to detect single-point mutations. This method addresses the quality and consistency of the tertiary and quaternary struct...

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Detalles Bibliográficos
Autores principales: Musetti, Caterina, Bean, Mark F., Quinque, Geoffrey T., Kwiatkowski, Christopher, Szewczuk, Lawrence M., Baldoni, John, Zajac, Matthew A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6349355/
https://www.ncbi.nlm.nih.gov/pubmed/29369625
http://dx.doi.org/10.1021/acs.analchem.8b00180

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