Is it possible to reconstruct an accurate cell lineage using CRISPR recorders?

Cell lineages provide the framework for understanding how cell fates are decided during development. Describing cell lineages in most organisms is challenging; even a fruit fly larva has ~50,000 cells and a small mammal has >1 billion cells. Recently, the idea of applying CRISPR to induce mutatio...

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Detalles Bibliográficos
Autores principales: Salvador-Martínez, Irepan, Grillo, Marco, Averof, Michalis, Telford, Maximilian J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6349403/
https://www.ncbi.nlm.nih.gov/pubmed/30688650
http://dx.doi.org/10.7554/eLife.40292

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6349403/
https://www.ncbi.nlm.nih.gov/pubmed/30688650
http://dx.doi.org/10.7554/eLife.40292

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