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Transducin-like enhancer of split 3 regulates proliferation of melanoma cells via histone deacetylase activity

Melanoma, one of the most aggressive neoplasms, is characterized by rapid cell proliferation. Transducin-like Enhancer of Split (TLE) is an important regulator of cell proliferation via Histone deacetylase (HDAC) recruitment. Given that HDAC activity is associated with melanoma progression, we exami...

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Detalles Bibliográficos
Autores principales: Ogawa, Masahiro, Yaginuma, Tatsuki, Nakatomi, Chihiro, Nakajima, Tsuyoshi, Tada-Shigeyama, Yukiyo, Addison, William N., Urata, Mariko, Matsubara, Takuma, Watanabe, Koji, Matsuo, Kou, Sato, Tsuyoshi, Honda, Hiromi, Hikiji, Hisako, Watanabe, Seiji, Kokabu, Shoichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6349449/
https://www.ncbi.nlm.nih.gov/pubmed/30719233
http://dx.doi.org/10.18632/oncotarget.26552