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Splicing modulator FR901464 is a potential agent for colorectal cancer in combination therapy

FR901464 (FR) was first described as an anticancer drug and later identified as a modulator of splicing factor 3B subunit 1 (SF3B1). Although the effectiveness of splicing modulators has been investigated in colorectal cancer (CRC) cells, their usefulness in animal experiments has not been confirmed...

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Detalles Bibliográficos
Autores principales:	Yamano, Tomoki, Kubo, Shuji, Yano, Aya, Kominato, Tomoko, Tanaka, Shino, Ikeda, Masataka, Tomita, Naohiro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2019
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6349454/ https://www.ncbi.nlm.nih.gov/pubmed/30719229 http://dx.doi.org/10.18632/oncotarget.26564

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