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Biological function and molecular mechanism of piRNA in cancer
Cancer is the second leading cause of death globally. piRNAs, which are a novel type of identified small noncoding RNA (ncRNA), play a crucial role in cancer genomics. In recent years, a relatively large number of studies have demonstrated that several piRNA are aberrantly expressed in various kinds...
| Autores principales: | , , , , , , , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6349561/ https://www.ncbi.nlm.nih.gov/pubmed/30705933 http://dx.doi.org/10.1016/j.plabm.2018.e00113 |
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| author | Chalbatani, Ghanbar Mahmoodi Dana, Hassan Memari, Feridon Gharagozlou, Elahe Ashjaei, Shirin Kheirandish, Peyman Marmari, Vahid Mahmoudzadeh, Habibollah Mozayani, Farnaz Maleki, Ali Reza Sadeghian, Ehsan Nia, Elham Zainali Miri, Seyed Rohollah Nia, Neda zainali Rezaeian, Omid Eskandary, Anahita Razavi, Narges Shirkhoda, Mohammad Rouzbahani, Fatemeh Nouri |
| author_facet | Chalbatani, Ghanbar Mahmoodi Dana, Hassan Memari, Feridon Gharagozlou, Elahe Ashjaei, Shirin Kheirandish, Peyman Marmari, Vahid Mahmoudzadeh, Habibollah Mozayani, Farnaz Maleki, Ali Reza Sadeghian, Ehsan Nia, Elham Zainali Miri, Seyed Rohollah Nia, Neda zainali Rezaeian, Omid Eskandary, Anahita Razavi, Narges Shirkhoda, Mohammad Rouzbahani, Fatemeh Nouri |
| author_sort | Chalbatani, Ghanbar Mahmoodi |
| collection | PubMed |
| description | Cancer is the second leading cause of death globally. piRNAs, which are a novel type of identified small noncoding RNA (ncRNA), play a crucial role in cancer genomics. In recent years, a relatively large number of studies have demonstrated that several piRNA are aberrantly expressed in various kinds of cancers including gastric cancer, bladder cancer, breast cancer, colorectal cancer and Lung cancer and may probably serve as a novel therapeutic target and biomarker for cancer treatment. The present review summarized current advances in our knowledge of the roles of piRNAs in cancer. |
| format | Online Article Text |
| id | pubmed-6349561 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2018 |
| publisher | Elsevier |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-63495612019-01-31 Biological function and molecular mechanism of piRNA in cancer Chalbatani, Ghanbar Mahmoodi Dana, Hassan Memari, Feridon Gharagozlou, Elahe Ashjaei, Shirin Kheirandish, Peyman Marmari, Vahid Mahmoudzadeh, Habibollah Mozayani, Farnaz Maleki, Ali Reza Sadeghian, Ehsan Nia, Elham Zainali Miri, Seyed Rohollah Nia, Neda zainali Rezaeian, Omid Eskandary, Anahita Razavi, Narges Shirkhoda, Mohammad Rouzbahani, Fatemeh Nouri Pract Lab Med Article Cancer is the second leading cause of death globally. piRNAs, which are a novel type of identified small noncoding RNA (ncRNA), play a crucial role in cancer genomics. In recent years, a relatively large number of studies have demonstrated that several piRNA are aberrantly expressed in various kinds of cancers including gastric cancer, bladder cancer, breast cancer, colorectal cancer and Lung cancer and may probably serve as a novel therapeutic target and biomarker for cancer treatment. The present review summarized current advances in our knowledge of the roles of piRNAs in cancer. Elsevier 2018-12-07 /pmc/articles/PMC6349561/ /pubmed/30705933 http://dx.doi.org/10.1016/j.plabm.2018.e00113 Text en © 2018 The Authors http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). |
| spellingShingle | Article Chalbatani, Ghanbar Mahmoodi Dana, Hassan Memari, Feridon Gharagozlou, Elahe Ashjaei, Shirin Kheirandish, Peyman Marmari, Vahid Mahmoudzadeh, Habibollah Mozayani, Farnaz Maleki, Ali Reza Sadeghian, Ehsan Nia, Elham Zainali Miri, Seyed Rohollah Nia, Neda zainali Rezaeian, Omid Eskandary, Anahita Razavi, Narges Shirkhoda, Mohammad Rouzbahani, Fatemeh Nouri Biological function and molecular mechanism of piRNA in cancer |
| title | Biological function and molecular mechanism of piRNA in cancer |
| title_full | Biological function and molecular mechanism of piRNA in cancer |
| title_fullStr | Biological function and molecular mechanism of piRNA in cancer |
| title_full_unstemmed | Biological function and molecular mechanism of piRNA in cancer |
| title_short | Biological function and molecular mechanism of piRNA in cancer |
| title_sort | biological function and molecular mechanism of pirna in cancer |
| topic | Article |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6349561/ https://www.ncbi.nlm.nih.gov/pubmed/30705933 http://dx.doi.org/10.1016/j.plabm.2018.e00113 |
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