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Amplified Host Defense by Toll-Like Receptor-Mediated Downregulation of the Glucocorticoid-Induced Leucine Zipper (GILZ) in Macrophages
Activation of toll-like receptors (TLRs) plays a pivotal role in the host defense against bacteria and results in the activation of NF-κB-mediated transcription of proinflammatory mediators. Glucocorticoid-induced leucine zipper (GILZ) is an anti-inflammatory mediator, which inhibits NF-κB activity...
Autores principales: | Hoppstädter, Jessica, Diesel, Britta, Linnenberger, Rebecca, Hachenthal, Nina, Flamini, Sara, Minet, Marie, Leidinger, Petra, Backes, Christina, Grässer, Friedrich, Meese, Eckart, Bruscoli, Stefano, Riccardi, Carlo, Huwer, Hanno, Kiemer, Alexandra K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6349698/ https://www.ncbi.nlm.nih.gov/pubmed/30723476 http://dx.doi.org/10.3389/fimmu.2018.03111 |
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