Cargando…
Loss of Neurofascin-186 Disrupts Alignment of AnkyrinG Relative to Its Binding Partners in the Axon Initial Segment
The axon initial segment (AIS) is a specialized region within the proximal portion of the axon that initiates action potentials thanks in large part to an enrichment of sodium channels. The scaffolding protein ankyrinG (AnkG) is essential for the recruitment of sodium channels as well as several oth...
Autores principales: | Alpizar, Scott A., Baker, Arielle L., Gulledge, Allan T., Hoppa, Michael B. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6349729/ https://www.ncbi.nlm.nih.gov/pubmed/30723396 http://dx.doi.org/10.3389/fncel.2019.00001 |
Ejemplares similares
-
AnkyrinG is required for maintenance of the axon initial segment and neuronal polarity
por: Hedstrom, Kristian L., et al.
Publicado: (2008) -
βIV spectrin is recruited to axon initial segments and nodes of Ranvier by ankyrinG
por: Yang, Yang, et al.
Publicado: (2007) -
Cannabinoid Receptors Modulate Neuronal Morphology and AnkyrinG Density at the Axon Initial Segment
por: Tapia, Mónica, et al.
Publicado: (2017) -
NuMA1 facilitates the assembly of the axon initial segment by promoting the retention of neurofascin-186
por: Abouelezz, Amr, et al.
Publicado: (2020) -
Structural basis for the membrane association of ankyrinG via palmitoylation
por: Fujiwara, Yuichiro, et al.
Publicado: (2016)