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CXCL13/CXCR5 Axis Predicts Poor Prognosis and Promotes Progression Through PI3K/AKT/mTOR Pathway in Clear Cell Renal Cell Carcinoma

The chemokine ligands and their receptors play critical roles in cancer progression and patients outcomes. We found that CXCL13 was significantly upregulated in ccRCC tissues compared with normal tissues in both The Cancer Genome Atlas (TCGA) cohort and a validated cohort of 90 pairs ccRCC tissues....

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Detalles Bibliográficos
Autores principales: Zheng, Zaosong, Cai, Yuhong, Chen, Haicheng, Chen, Zhiliang, Zhu, Dingjun, Zhong, Qiyu, Xie, Wenlian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6349755/
https://www.ncbi.nlm.nih.gov/pubmed/30723697
http://dx.doi.org/10.3389/fonc.2018.00682