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FOXP3+ Regulatory T Cell Compartment Is Altered in Children With Newly Diagnosed Type 1 Diabetes but Not in Autoantibody-Positive at-Risk Children

The dysfunction of FOXP3-positive regulatory T cells (Tregs) plays a key role in the pathogenesis of autoimmune diseases, including type 1 diabetes (T1D). However, previous studies analyzing the peripheral blood Treg compartment in patients with T1D have yielded partially conflicting results. Moreov...

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Detalles Bibliográficos
Autores principales:	Viisanen, Tyyne, Gazali, Ahmad M., Ihantola, Emmi-Leena, Ekman, Ilse, Näntö-Salonen, Kirsti, Veijola, Riitta, Toppari, Jorma, Knip, Mikael, Ilonen, Jorma, Kinnunen, Tuure
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6349758/ https://www.ncbi.nlm.nih.gov/pubmed/30723474 http://dx.doi.org/10.3389/fimmu.2019.00019

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