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Venous identity requires BMP signalling through ALK3

Venous endothelial cells are molecularly and functionally distinct from their arterial counterparts. Although veins are often considered the default endothelial state, genetic manipulations can modulate both acquisition and loss of venous fate, suggesting that venous identity is the result of active...

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Detalles Bibliográficos
Autores principales: Neal, Alice, Nornes, Svanhild, Payne, Sophie, Wallace, Marsha D., Fritzsche, Martin, Louphrasitthiphol, Pakavarin, Wilkinson, Robert N., Chouliaras, Kira M., Liu, Ke, Plant, Karen, Sholapurkar, Radhika, Ratnayaka, Indrika, Herzog, Wiebke, Bond, Gareth, Chico, Tim, Bou-Gharios, George, De Val, Sarah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6349860/
https://www.ncbi.nlm.nih.gov/pubmed/30692543
http://dx.doi.org/10.1038/s41467-019-08315-w