Differential effects of N-acetylcysteine on retinal degeneration in two mouse models of normal tension glaucoma

N-acetylcysteine (NAC) is widely used as a mucolytic agent and as an antidote to paracetamol overdose. NAC serves as a precursor of cysteine and stimulates the synthesis of glutathione in neural cells. Suppressing oxidative stress in the retina may be an effective therapeutic strategy for glaucoma,...

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Detalles Bibliográficos
Autores principales: Sano, Hiroki, Namekata, Kazuhiko, Kimura, Atsuko, Shitara, Hiroshi, Guo, Xiaoli, Harada, Chikako, Mitamura, Yoshinori, Harada, Takayuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6349904/
https://www.ncbi.nlm.nih.gov/pubmed/30692515
http://dx.doi.org/10.1038/s41419-019-1365-z

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