DeepSeqPan, a novel deep convolutional neural network model for pan-specific class I HLA-peptide binding affinity prediction

Interactions between human leukocyte antigens (HLAs) and peptides play a critical role in the human immune system. Accurate computational prediction of HLA-binding peptides can be used for peptide drug discovery. Currently, the best prediction algorithms are neural network-based pan-specific models,...

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Detalles Bibliográficos
Autores principales: Liu, Zhonghao, Cui, Yuxin, Xiong, Zheng, Nasiri, Alierza, Zhang, Ansi, Hu, Jianjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6349913/
https://www.ncbi.nlm.nih.gov/pubmed/30692623
http://dx.doi.org/10.1038/s41598-018-37214-1

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