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Amide nitrogen pyramidalization changes lactam amide spinning

Although cis-trans lactam amide rotation is fundamentally important, it has been little studied, except for a report on peptide-based lactams. Here, we find a consistent relationship between the lactam amide cis/trans ratios and the rotation rates between the trans and cis lactam amides upon the lac...

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Detalles Bibliográficos
Autores principales:	Otani, Yuko, Liu, Xin, Ohno, Hisashi, Wang, Siyuan, Zhai, Luhan, Su, Aoze, Kawahata, Masatoshi, Yamaguchi, Kentaro, Ohwada, Tomohiko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6349922/ https://www.ncbi.nlm.nih.gov/pubmed/30692534 http://dx.doi.org/10.1038/s41467-018-08249-9

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