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Antigen Production After Latency Reversal and Expression of Inhibitory Receptors in CD8+ T Cells Limit the Killing of HIV-1 Reactivated Cells

The so-called shock and kill therapies aim to combine HIV-1 reactivation by latency-reversing agents (LRA) with immune clearance to purge the HIV-1 reservoir. The clinical use of LRA has demonstrated detectable perturbations in the HIV-1 reservoir without measurable reductions to date. Consequently,...

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Detalles Bibliográficos
Autores principales:	Ruiz, Alba, Blanch-Lombarte, Oscar, Jimenez-Moyano, Esther, Ouchi, Dan, Mothe, Beatriz, Peña, Ruth, Galvez, Cristina, Genescà, Meritxell, Martinez-Picado, Javier, Goulder, Philip, Barnard, Richard, Howell, Bonnie, Clotet, Bonaventura, Prado, Julia G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6349966/ https://www.ncbi.nlm.nih.gov/pubmed/30723480 http://dx.doi.org/10.3389/fimmu.2018.03162

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