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Strain-specific differences in the development of bone loss and incidence of osteonecrosis following glucocorticoid treatment in two different mouse strains

OBJECTIVE: Glucocorticoids (GCs) are commonly prescribed as treatment for chronic inflammatory diseases. Prolonged use of GCs is a common cause of atraumatic osteonecrosis (ON) and secondary osteoporosis. Currently, there is no effective treatment for this disease; therefore, a reliable animal model...

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Detalles Bibliográficos
Autores principales: Shidara, Kie, Mohan, Geetha, Evan Lay, Yan-An, Jepsen, Karl J., Yao, Wei, Lane, Nancy E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chinese Speaking Orthopaedic Society 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6350024/
https://www.ncbi.nlm.nih.gov/pubmed/30723686
http://dx.doi.org/10.1016/j.jot.2018.07.001

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