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Strain-specific differences in the development of bone loss and incidence of osteonecrosis following glucocorticoid treatment in two different mouse strains
OBJECTIVE: Glucocorticoids (GCs) are commonly prescribed as treatment for chronic inflammatory diseases. Prolonged use of GCs is a common cause of atraumatic osteonecrosis (ON) and secondary osteoporosis. Currently, there is no effective treatment for this disease; therefore, a reliable animal model...
Autores principales: | Shidara, Kie, Mohan, Geetha, Evan Lay, Yan-An, Jepsen, Karl J., Yao, Wei, Lane, Nancy E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Chinese Speaking Orthopaedic Society
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6350024/ https://www.ncbi.nlm.nih.gov/pubmed/30723686 http://dx.doi.org/10.1016/j.jot.2018.07.001 |
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