Cargando…

JNK signalling mediates aspects of maternal immune activation: importance of maternal genotype in relation to schizophrenia risk

BACKGROUND: Important insight into the mechanisms through which gene-environmental interactions cause schizophrenia can be achieved through preclinical studies combining prenatal immune stimuli with disease-related genetic risk modifications. Accumulating evidence associates JNK signalling molecules...

Descripción completa

Detalles Bibliográficos
Autores principales:	Openshaw, Rebecca L., Kwon, Jaedeok, McColl, Alison, Penninger, Josef M., Cavanagh, Jonathan, Pratt, Judith A., Morris, Brian J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6350402/ https://www.ncbi.nlm.nih.gov/pubmed/30691477 http://dx.doi.org/10.1186/s12974-019-1408-5

Ejemplares similares

Distinct trans-placental effects of maternal immune activation by TLR3 and TLR7 agonists: implications for schizophrenia risk
por: Kwon, Jaedeok, et al.
Publicado: (2021)

Differential Effects of Toll-Like Receptor Activation and Differential Mediation by MAP Kinases of Immune Responses in Microglial Cells
por: Kwon, Jaedeok, et al.
Publicado: (2021)

Map2k7 Haploinsufficiency Induces Brain Imaging Endophenotypes and Behavioral Phenotypes Relevant to Schizophrenia
por: Openshaw, Rebecca L, et al.
Publicado: (2020)

The schizophrenia risk gene Map2k7 regulates responding in a novel contingency-shifting rodent touchscreen gambling task
por: Openshaw, Rebecca L., et al.
Publicado: (2022)

Mice haploinsufficient for Map2k7, a gene involved in neurodevelopment and risk for schizophrenia, show impaired attention, a vigilance decrement deficit and unstable cognitive processing in an attentional task: impact of minocycline
por: Openshaw, R.L., et al.
Publicado: (2016)

BDNF and JNK Signaling Modulate Cortical Interneuron and Perineuronal Net Development: Implications for Schizophrenia-Linked 16p11.2 Duplication Syndrome
por: Willis, Ashleigh, et al.
Publicado: (2020)

Evidence for Maternal-Fetal Genotype Incompatibility as a Risk Factor for Schizophrenia
por: Palmer, Christina G. S.
Publicado: (2010)

A. The Maternal Aspect
por: Stirling, Hugh
Publicado: (1947)

Developmental aspects of maternal-fetal, and infant gut microbiota and implications for long-term health
por: Neu, Josef
Publicado: (2015)

The Systemic Response to Topical Aldara Treatment is Mediated Through Direct TLR7 Stimulation as Imiquimod Enters the Circulation
por: Nerurkar, Louis, et al.
Publicado: (2017)

Interventions to change maternity healthcare professionals’ behaviours to promote weight-related support for obese pregnant women: a systematic review
por: Heslehurst, Nicola, et al.
Publicado: (2014)

The importance of colostrum in maternal care and its formation in mammalian species
por: Baumrucker, Craig R, et al.
Publicado: (2023)

Dysregulation of Amino Acid Transporters in a Rat Model of TLR7-Mediated Maternal Immune Activation
por: McColl, Eliza R., et al.
Publicado: (2023)

Hyperthyroidism in the pregnant woman: Maternal and fetal aspects
por: Moleti, Mariacarla, et al.
Publicado: (2019)

Immunobiological aspects of vaccines in pregnancy: Maternal perspective
por: Chu, Helen Y., et al.
Publicado: (2020)

Epidemiological Aspects of Maternal and Congenital Toxoplasmosis in Panama
por: Flores, Carlos, et al.
Publicado: (2021)

Effect of maternal infection on progeny growth and resistance mediated by maternal genotype and nutrient availability
por: Höckerstedt, Layla, et al.
Publicado: (2021)

Peripheral inflammation is associated with remote global gene expression changes in the brain
por: Thomson, Carolyn A, et al.
Publicado: (2014)

Sustained exposure to systemic endotoxin triggers chemokine induction in the brain followed by a rapid influx of leukocytes
por: Thomson, Carolyn A., et al.
Publicado: (2020)

Aspects of embryo-maternal communication in establishment of pregnancy in cattle
por: Sánchez, José M., et al.
Publicado: (2019)

Importance of Maternal Persistence in Young Children's Persistence
por: Imafuku, Masahiro, et al.
Publicado: (2021)

Tianeptine Affects the Improvement of Behavioral Defects, such as Schizophrenia, Caused by Maternal Immune Activation in the Mice Offspring
por: Jung, Kooseung, et al.
Publicado: (2023)

Mice lacking melatonin MT2 receptors exhibit attentional deficits, anxiety and enhanced social interaction
por: Thomson, David M, et al.
Publicado: (2021)

Maternity Service in Bristol: Some Aspects of Integration and Possible Development
por: Lennon, G. Gordon
Publicado: (1952)

The Maternal Mortality Problem in Some of Its Physiological and Medical Aspects
por: Nicholson, H. Oliphant
Publicado: (1935)

TLR7-mediated skin inflammation remotely triggers chemokine expression and leukocyte accumulation in the brain
por: McColl, Alison, et al.
Publicado: (2016)

Placental genotype affects early postpartum maternal behaviour
por: Gardner, Sarah, et al.
Publicado: (2019)

Maternal Lipids Are as Important as Glucose for Fetal Growth: Findings from the Pune Maternal Nutrition Study
por: Kulkarni, Smita R., et al.
Publicado: (2013)

Maternal Obesity and Patterns in Postnatal Diet, Physical Activity and Weight among a Highly Deprived Population in the UK: The GLOWING Pilot Trial
por: Heslehurst, Nicola, et al.
Publicado: (2023)

Microglia involvement in sex-dependent behaviors and schizophrenia occurrence in offspring with maternal dexamethasone exposure
por: Rim, Chan, et al.
Publicado: (2022)

GestationaL Obesity Weight management: Implementation of National Guidelines (GLOWING): a pilot cluster randomised controlled trial of a guideline implementation intervention for the management of maternal obesity by midwives
por: Heslehurst, Nicola, et al.
Publicado: (2018)

Maternity Charities, the Edinburgh Maternity Scheme and the Medicalisation of Childbirth, 1900–1925
por: Nuttall, Alison
Publicado: (2011)

The importance of maternal insulin resistance throughout pregnancy on neonatal adiposity
por: Lima, Rodrigo A., et al.
Publicado: (2020)

Maternal care affects the phenotype of a rat model for schizophrenia
por: van Vugt, Ruben W. M., et al.
Publicado: (2014)

Maternal Immune Activation and Schizophrenia–Evidence for an Immune Priming Disorder
por: Choudhury, Zahra, et al.
Publicado: (2021)

Maternal immune activation induces methylation changes in schizophrenia genes
por: Johnson, Thomas, et al.
Publicado: (2022)

The importance of maternity leave in the health service. An interview with the Head of the Maternity Office, Federal Ministry for Family Affairs
por: Struck, Jutta
Publicado: (2012)

The Population Problem: The Importance of Maternal Mortality as a Factor
Publicado: (1915)

Optimizing Maternal Nutrition: The Importance of a Tailored Approach
por: Brink, Lauren R, et al.
Publicado: (2022)

Maternal and perinatal aspects of birth defects: a case-control study
por: Nhoncanse, Geiza César, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_jb6eu9p9c7ue5laaef08ge0eml