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Fully Convolutional DenseNet with Multiscale Context for Automated Breast Tumor Segmentation

Breast tumor segmentation plays a crucial role in subsequent disease diagnosis, and most algorithms need interactive prior to firstly locate tumors and perform segmentation based on tumor-centric candidates. In this paper, we propose a fully convolutional network to achieve automatic segmentation of...

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Detalles Bibliográficos
Autores principales: Hai, Jinjin, Qiao, Kai, Chen, Jian, Tan, Hongna, Xu, Jingbo, Zeng, Lei, Shi, Dapeng, Yan, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6350548/
https://www.ncbi.nlm.nih.gov/pubmed/30774849
http://dx.doi.org/10.1155/2019/8415485
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author Hai, Jinjin
Qiao, Kai
Chen, Jian
Tan, Hongna
Xu, Jingbo
Zeng, Lei
Shi, Dapeng
Yan, Bin
author_facet Hai, Jinjin
Qiao, Kai
Chen, Jian
Tan, Hongna
Xu, Jingbo
Zeng, Lei
Shi, Dapeng
Yan, Bin
author_sort Hai, Jinjin
collection PubMed
description Breast tumor segmentation plays a crucial role in subsequent disease diagnosis, and most algorithms need interactive prior to firstly locate tumors and perform segmentation based on tumor-centric candidates. In this paper, we propose a fully convolutional network to achieve automatic segmentation of breast tumor in an end-to-end manner. Considering the diversity of shape and size for malignant tumors in the digital mammograms, we introduce multiscale image information into the fully convolutional dense network architecture to improve the segmentation precision. Multiple sampling rates of atrous convolution are concatenated to acquire different field-of-views of image features without adding additional number of parameters to avoid over fitting. Weighted loss function is also employed during training according to the proportion of the tumor pixels in the entire image, in order to weaken unbalanced classes problem. Qualitative and quantitative comparisons demonstrate that the proposed algorithm can achieve automatic tumor segmentation and has high segmentation precision for various size and shapes of tumor images without preprocessing and postprocessing.
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spelling pubmed-63505482019-02-17 Fully Convolutional DenseNet with Multiscale Context for Automated Breast Tumor Segmentation Hai, Jinjin Qiao, Kai Chen, Jian Tan, Hongna Xu, Jingbo Zeng, Lei Shi, Dapeng Yan, Bin J Healthc Eng Research Article Breast tumor segmentation plays a crucial role in subsequent disease diagnosis, and most algorithms need interactive prior to firstly locate tumors and perform segmentation based on tumor-centric candidates. In this paper, we propose a fully convolutional network to achieve automatic segmentation of breast tumor in an end-to-end manner. Considering the diversity of shape and size for malignant tumors in the digital mammograms, we introduce multiscale image information into the fully convolutional dense network architecture to improve the segmentation precision. Multiple sampling rates of atrous convolution are concatenated to acquire different field-of-views of image features without adding additional number of parameters to avoid over fitting. Weighted loss function is also employed during training according to the proportion of the tumor pixels in the entire image, in order to weaken unbalanced classes problem. Qualitative and quantitative comparisons demonstrate that the proposed algorithm can achieve automatic tumor segmentation and has high segmentation precision for various size and shapes of tumor images without preprocessing and postprocessing. Hindawi 2019-01-14 /pmc/articles/PMC6350548/ /pubmed/30774849 http://dx.doi.org/10.1155/2019/8415485 Text en Copyright © 2019 Jinjin Hai et al. http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Hai, Jinjin
Qiao, Kai
Chen, Jian
Tan, Hongna
Xu, Jingbo
Zeng, Lei
Shi, Dapeng
Yan, Bin
Fully Convolutional DenseNet with Multiscale Context for Automated Breast Tumor Segmentation
title Fully Convolutional DenseNet with Multiscale Context for Automated Breast Tumor Segmentation
title_full Fully Convolutional DenseNet with Multiscale Context for Automated Breast Tumor Segmentation
title_fullStr Fully Convolutional DenseNet with Multiscale Context for Automated Breast Tumor Segmentation
title_full_unstemmed Fully Convolutional DenseNet with Multiscale Context for Automated Breast Tumor Segmentation
title_short Fully Convolutional DenseNet with Multiscale Context for Automated Breast Tumor Segmentation
title_sort fully convolutional densenet with multiscale context for automated breast tumor segmentation
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6350548/
https://www.ncbi.nlm.nih.gov/pubmed/30774849
http://dx.doi.org/10.1155/2019/8415485
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