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Novel Role of Dehydrated Human Amnion/Chorion Membrane in Healing of Denuded Ureter in Robot-Assisted Excision of Endometriosis

Ureteral injury is an uncommon but potentially morbid complication following any open or endoscopic pelvic procedure. Gynecologic surgeries alone make up 50 percent of nonurologic ureteral injuries leading to prolonged hospital stays, secondary interventions, and potential loss of renal function. Th...

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Detalles Bibliográficos
Autores principales: Hasan, Osamah, Johnson, Grant S., Siegert, James J., Garcini, Francisco, Nguyen, Thai T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6350570/
https://www.ncbi.nlm.nih.gov/pubmed/30766738
http://dx.doi.org/10.1155/2019/1920430
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author Hasan, Osamah
Johnson, Grant S.
Siegert, James J.
Garcini, Francisco
Nguyen, Thai T.
author_facet Hasan, Osamah
Johnson, Grant S.
Siegert, James J.
Garcini, Francisco
Nguyen, Thai T.
author_sort Hasan, Osamah
collection PubMed
description Ureteral injury is an uncommon but potentially morbid complication following any open or endoscopic pelvic procedure. Gynecologic surgeries alone make up 50 percent of nonurologic ureteral injuries leading to prolonged hospital stays, secondary interventions, and potential loss of renal function. The use of AmnioFix ® a processed dehydrated, immunologically privileged cellular amniotic membrane allograft has been well established in urologic and gynecologic procedures. These allografts contain human extracellular matrix components, growth factors, and cytokines that mediate inflammation and facilitate would healing. We report the first application of AmnioFix on a denuded ureter during a case of robotic-assisted excision of endometriosis. We include a literature review and discussion on the management outcomes of iatrogenic injury to the ureters.
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spelling pubmed-63505702019-02-14 Novel Role of Dehydrated Human Amnion/Chorion Membrane in Healing of Denuded Ureter in Robot-Assisted Excision of Endometriosis Hasan, Osamah Johnson, Grant S. Siegert, James J. Garcini, Francisco Nguyen, Thai T. Case Rep Obstet Gynecol Case Report Ureteral injury is an uncommon but potentially morbid complication following any open or endoscopic pelvic procedure. Gynecologic surgeries alone make up 50 percent of nonurologic ureteral injuries leading to prolonged hospital stays, secondary interventions, and potential loss of renal function. The use of AmnioFix ® a processed dehydrated, immunologically privileged cellular amniotic membrane allograft has been well established in urologic and gynecologic procedures. These allografts contain human extracellular matrix components, growth factors, and cytokines that mediate inflammation and facilitate would healing. We report the first application of AmnioFix on a denuded ureter during a case of robotic-assisted excision of endometriosis. We include a literature review and discussion on the management outcomes of iatrogenic injury to the ureters. Hindawi 2019-01-15 /pmc/articles/PMC6350570/ /pubmed/30766738 http://dx.doi.org/10.1155/2019/1920430 Text en Copyright © 2019 Osamah Hasan et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Hasan, Osamah
Johnson, Grant S.
Siegert, James J.
Garcini, Francisco
Nguyen, Thai T.
Novel Role of Dehydrated Human Amnion/Chorion Membrane in Healing of Denuded Ureter in Robot-Assisted Excision of Endometriosis
title Novel Role of Dehydrated Human Amnion/Chorion Membrane in Healing of Denuded Ureter in Robot-Assisted Excision of Endometriosis
title_full Novel Role of Dehydrated Human Amnion/Chorion Membrane in Healing of Denuded Ureter in Robot-Assisted Excision of Endometriosis
title_fullStr Novel Role of Dehydrated Human Amnion/Chorion Membrane in Healing of Denuded Ureter in Robot-Assisted Excision of Endometriosis
title_full_unstemmed Novel Role of Dehydrated Human Amnion/Chorion Membrane in Healing of Denuded Ureter in Robot-Assisted Excision of Endometriosis
title_short Novel Role of Dehydrated Human Amnion/Chorion Membrane in Healing of Denuded Ureter in Robot-Assisted Excision of Endometriosis
title_sort novel role of dehydrated human amnion/chorion membrane in healing of denuded ureter in robot-assisted excision of endometriosis
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6350570/
https://www.ncbi.nlm.nih.gov/pubmed/30766738
http://dx.doi.org/10.1155/2019/1920430
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