Rapid Production of Human VEGF-A following Intradermal Injection of Modified VEGF-A mRNA Demonstrated by Cutaneous Microdialysis in the Rabbit and Pig In Vivo

Chemically modified mRNA is a novel, highly efficient, biocompatible modality for therapeutic protein expression that may overcome the challenges and safety concerns with current gene therapy strategies. We explored the efficiency of intradermally injected modified VEGF-A(165) mRNA (VEGF-A mRNA) for...

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Detalles Bibliográficos
Autores principales: Pehrsson, Susanne, Hölttä, Mikko, Linhardt, Gunilla, Danielson, Regina Fritsche, Carlsson, Leif
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6350593/
https://www.ncbi.nlm.nih.gov/pubmed/30766883
http://dx.doi.org/10.1155/2019/3915851

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