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Structure–activity relationship of an antimicrobial peptide, Phylloseptin-PHa: balance of hydrophobicity and charge determines the selectivity of bioactivities

BACKGROUND: Antimicrobial peptides (AMPs) from the skin secretions of amphibians are now considered as a potential alternative to conventional antibiotics. Phylloseptins are a family of AMPs identified in the skin secretions of Phyllomedusinae tree frogs which exhibit highly conserved structural cha...

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Detalles Bibliográficos
Autores principales:	Liu, Yuzhang, Du, Qiang, Ma, Chengbang, Xi, Xinping, Wang, Lei, Zhou, Mei, Burrows, James F, Chen, Tianbao, Wang, Hui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2019
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6350648/ https://www.ncbi.nlm.nih.gov/pubmed/30774309 http://dx.doi.org/10.2147/DDDT.S191072

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