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Qualitative evidence synthesis for complex interventions and guideline development: clarification of the purpose, designs and relevant methods

This paper is one of a series exploring the implications of complexity for systematic reviews and guideline development, commissioned by the WHO. The paper specifically explores the role of qualitative evidence synthesis. Qualitative evidence synthesis is the broad term for the group of methods used...

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Detalles Bibliográficos
Autores principales: Flemming, Kate, Booth, Andrew, Garside, Ruth, Tunçalp, Özge, Noyes, Jane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6350756/
https://www.ncbi.nlm.nih.gov/pubmed/30775015
http://dx.doi.org/10.1136/bmjgh-2018-000882
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author Flemming, Kate
Booth, Andrew
Garside, Ruth
Tunçalp, Özge
Noyes, Jane
author_facet Flemming, Kate
Booth, Andrew
Garside, Ruth
Tunçalp, Özge
Noyes, Jane
author_sort Flemming, Kate
collection PubMed
description This paper is one of a series exploring the implications of complexity for systematic reviews and guideline development, commissioned by the WHO. The paper specifically explores the role of qualitative evidence synthesis. Qualitative evidence synthesis is the broad term for the group of methods used to undertake systematic reviews of qualitative research evidence. As an approach, qualitative evidence synthesis is increasingly recognised as having a key role to play in addressing questions relating to intervention or system complexity, and guideline development processes. This is due to the unique role qualitative research can play in establishing the relative importance of outcomes, the acceptability, fidelity and reach of interventions, their feasibility in different settings and potential consequences on equity across populations. This paper outlines the purpose of qualitative evidence synthesis, provides detail of how qualitative evidence syntheses can help establish understanding and explanation of the complexity that can occur in relation to both interventions and systems, and how qualitative evidence syntheses can contribute to evidence to decision frameworks. It provides guidance for the choice of qualitative evidence synthesis methods in the context of guideline development for complex interventions, giving ‘real life’ examples of where this has occurred. Information to support decision-making around choice qualitative evidence synthesis methods in the context of guideline development is provided. Approaches for reporting qualitative evidence syntheses are discussed alongside mechanisms for assessing confidence in the findings of a review.
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spelling pubmed-63507562019-02-15 Qualitative evidence synthesis for complex interventions and guideline development: clarification of the purpose, designs and relevant methods Flemming, Kate Booth, Andrew Garside, Ruth Tunçalp, Özge Noyes, Jane BMJ Glob Health Analysis This paper is one of a series exploring the implications of complexity for systematic reviews and guideline development, commissioned by the WHO. The paper specifically explores the role of qualitative evidence synthesis. Qualitative evidence synthesis is the broad term for the group of methods used to undertake systematic reviews of qualitative research evidence. As an approach, qualitative evidence synthesis is increasingly recognised as having a key role to play in addressing questions relating to intervention or system complexity, and guideline development processes. This is due to the unique role qualitative research can play in establishing the relative importance of outcomes, the acceptability, fidelity and reach of interventions, their feasibility in different settings and potential consequences on equity across populations. This paper outlines the purpose of qualitative evidence synthesis, provides detail of how qualitative evidence syntheses can help establish understanding and explanation of the complexity that can occur in relation to both interventions and systems, and how qualitative evidence syntheses can contribute to evidence to decision frameworks. It provides guidance for the choice of qualitative evidence synthesis methods in the context of guideline development for complex interventions, giving ‘real life’ examples of where this has occurred. Information to support decision-making around choice qualitative evidence synthesis methods in the context of guideline development is provided. Approaches for reporting qualitative evidence syntheses are discussed alongside mechanisms for assessing confidence in the findings of a review. BMJ Publishing Group 2019-01-25 /pmc/articles/PMC6350756/ /pubmed/30775015 http://dx.doi.org/10.1136/bmjgh-2018-000882 Text en © World Health Organization 2019. Licensee BMJ. This is an open access article distributed under the terms of the Creative Commons Attribution-Non commercial IGO License (CC BY 3.0 IGO (https://creativecommons.org/licenses/by/3.0/igo/) ), which permits use, distribution, and reproduction for non-commercial purposes in any medium, provided the original work is properly cited. In any reproduction of this article there should not be any suggestion that WHO or this article endorse any specific organization or products. The use of the WHO logo is not permitted. This notice should be preserved along with the article’s original URL.
spellingShingle Analysis
Flemming, Kate
Booth, Andrew
Garside, Ruth
Tunçalp, Özge
Noyes, Jane
Qualitative evidence synthesis for complex interventions and guideline development: clarification of the purpose, designs and relevant methods
title Qualitative evidence synthesis for complex interventions and guideline development: clarification of the purpose, designs and relevant methods
title_full Qualitative evidence synthesis for complex interventions and guideline development: clarification of the purpose, designs and relevant methods
title_fullStr Qualitative evidence synthesis for complex interventions and guideline development: clarification of the purpose, designs and relevant methods
title_full_unstemmed Qualitative evidence synthesis for complex interventions and guideline development: clarification of the purpose, designs and relevant methods
title_short Qualitative evidence synthesis for complex interventions and guideline development: clarification of the purpose, designs and relevant methods
title_sort qualitative evidence synthesis for complex interventions and guideline development: clarification of the purpose, designs and relevant methods
topic Analysis
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6350756/
https://www.ncbi.nlm.nih.gov/pubmed/30775015
http://dx.doi.org/10.1136/bmjgh-2018-000882
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