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Synthesis and biological activity of methylated derivatives of the Pseudomonas metabolites HHQ, HQNO and PQS

Selectively methylated analogues of naturally occurring 2-heptyl-4(1H)-quinolones, which are alkaloids common within the Rutaceae family and moreover are associated with quorum sensing and virulence of the human pathogen Pseudomonas aeruginosa, have been prepared. While the synthesis by direct methy...

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Detalles Bibliográficos
Autores principales:	Thierbach, Sven, Wienhold, Max, Fetzner, Susanne, Hennecke, Ulrich
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Beilstein-Institut 2019
Materias:	Full Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6350858/ https://www.ncbi.nlm.nih.gov/pubmed/30745993 http://dx.doi.org/10.3762/bjoc.15.18

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