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CDK Phosphorylation of Translation Initiation Factors Couples Protein Translation with Cell-Cycle Transition

Protein translation in eukaryotes is cell-cycle dependent, with translation rates more robust in G1 phase of the cell cycle than in mitosis. However, whether the fundamental cell-cycle control machinery directly activates protein translation during the G1/S cell-cycle transition remains unknown. Usi...

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Detalles Bibliográficos
Autores principales: An, Tai, Liu, Yi, Gourguechon, Stéphane, Wang, Ching C., Li, Ziyin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6350937/
https://www.ncbi.nlm.nih.gov/pubmed/30540951
http://dx.doi.org/10.1016/j.celrep.2018.11.063