Abrogation of Stem Loop Binding Protein (Slbp) function leads to a failure of cells to transition from proliferation to differentiation, retinal coloboma and midline axon guidance deficits

Through forward genetic screening for mutations affecting visual system development, we identified prominent coloboma and cell-autonomous retinal neuron differentiation, lamination and retinal axon projection defects in eisspalte (ele) mutant zebrafish. Additional axonal deficits were present, most...

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Detalles Bibliográficos
Autores principales: Turner, Katherine J., Hoyle, Jacqueline, Valdivia, Leonardo E., Cerveny, Kara L., Hart, Wendy, Mangoli, Maryam, Geisler, Robert, Rees, Michele, Houart, Corinne, Poole, Richard J., Wilson, Stephen W., Gestri, Gaia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6350959/
https://www.ncbi.nlm.nih.gov/pubmed/30695021
http://dx.doi.org/10.1371/journal.pone.0211073

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