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Discovery of gene regulatory elements through a new bioinformatics analysis of haploid genetic screens

The systematic identification of regulatory elements that control gene expression remains a challenge. Genetic screens that use untargeted mutagenesis have the potential to identify protein-coding genes, non-coding RNAs and regulatory elements, but their analysis has mainly focused on identifying th...

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Detalles Bibliográficos
Autores principales: Patel, Bhaven B., Lebensohn, Andres M., Pusapati, Ganesh V., Carette, Jan E., Salzman, Julia, Rohatgi, Rajat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6350973/
https://www.ncbi.nlm.nih.gov/pubmed/30695034
http://dx.doi.org/10.1371/journal.pone.0198463