The TLR4 Agonist Immunomax Affects the Phenotype of Mouse Lung Macrophages during Respiratory Syncytial Virus Infection

In the study, the effect of the TLR4 agonist Immunomax was investigated in vitro and in vivo. In particular, Immunomax was shown to polarize mouse bone marrow macrophages from the M0 and M2 states into the M1 state (ARG1 and iNOS mRNA expression levels were used to identify the mouse M1 and M2 pheno...

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Detalles Bibliográficos
Autores principales: Nikonova, A. A., Pichugin, A. V., Chulkina, M. M., Lebedeva, E. S., Gaisina, A. R., Shilovskiy, I. P., Ataullakhanov, R. I., Khaitov, M. R., Khaitov, R. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: A.I. Gordeyev 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6351037/
https://www.ncbi.nlm.nih.gov/pubmed/30713767

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