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Polyploid Superficial Cells that Maintain the Urothelial Barrier Are Produced via Incomplete Cytokinesis and Endoreplication

The urothelium is an epithelia barrier lined by a luminal layer of binucleated, octoploid, superficial cells. Superficial cells are critical for production and transport of uroplakins, a family of proteins that assemble into a waterproof crystalline plaque that helps protect against infection and to...

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Detalles Bibliográficos
Autores principales: Wang, Jia, Batourina, Ekatherina, Schneider, Kerry, Souza, Spenser, Swayne, Theresa, Liu, Chang, George, Christopher D., Tate, Tiffany, Dan, Hanbin, Wiessner, Gregory, Zhuravlev, Yelena, Canman, Julie C., Mysorekar, Indira U., Lee Mendelsohn, Cathy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6351079/
https://www.ncbi.nlm.nih.gov/pubmed/30304685
http://dx.doi.org/10.1016/j.celrep.2018.09.042