Global role for coactivator complexes in RNA polymerase II transcription

SAGA and TFIID are related transcription complexes, which were proposed to alternatively deliver TBP at different promoter classes. Recent genome-wide studies in yeast revealed that both complexes are required for the transcription of a vast majority of genes by RNA polymerase II raising new questio...

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Detalles Bibliográficos
Autores principales: Fischer, Veronique, Schumacher, Kenny, Tora, Laszlo, Devys, Didier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Point-of-View
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6351120/
https://www.ncbi.nlm.nih.gov/pubmed/30299209
http://dx.doi.org/10.1080/21541264.2018.1521214
Descripción
Sumario:SAGA and TFIID are related transcription complexes, which were proposed to alternatively deliver TBP at different promoter classes. Recent genome-wide studies in yeast revealed that both complexes are required for the transcription of a vast majority of genes by RNA polymerase II raising new questions about the role of coactivators.

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