Mir223 restrains autophagy and promotes CNS inflammation by targeting ATG16L1

Microglia are innate immune cells in the central nervous system (CNS), that supplies neurons with key factors for executing autophagosomal/lysosomal functions. Macroautophagy/autophagy is a cellular catabolic process that maintains cell balance in response to stress-related stimulation. Abnormal aut...

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Detalles Bibliográficos
Autores principales: Li, Yan, Zhou, Dongmei, Ren, Yinghui, Zhang, Zimu, Guo, Xiangdong, Ma, MingKun, Xue, Zhenyi, Lv, Jienv, Liu, Hongkun, Xi, Qing, Jia, Long, Zhang, Lijuan, Liu, Ying, Zhang, Qi, Yan, Jun, Da, Yurong, Gao, Fei, Yue, Jianbo, Yao, Zhi, Zhang, Rongxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Research Paper - Basic Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6351131/
https://www.ncbi.nlm.nih.gov/pubmed/30208760
http://dx.doi.org/10.1080/15548627.2018.1522467

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