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Pharmacological Blockade of Soluble Epoxide Hydrolase Attenuates the Progression of Congestive Heart Failure Combined With Chronic Kidney Disease: Insights From Studies With Fawn-Hooded Hypertensive Rats
An association between congestive heart failure (CHF) and chronic kidney disease (CKD) results in extremely poor patient survival rates. Previous studies have shown that increasing kidney epoxyeicosatrienoic acids (EETs) by blocking soluble epoxide hydrolase (sEH), an enzyme responsible for EETs deg...
Autores principales: | Vacková, Šárka, Kopkan, Libor, Kikerlová, Soňa, Husková, Zuzana, Sadowski, Janusz, Kompanowska-Jezierska, Elzbieta, Hammock, Bruce D., Imig, John D., Táborský, Miloš, Melenovský, Vojtěch, Červenka, Luděk |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6351500/ https://www.ncbi.nlm.nih.gov/pubmed/30728778 http://dx.doi.org/10.3389/fphar.2019.00018 |
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