S-nitrosylation of E3 ubiquitin-protein ligase RNF213 alters non-canonical Wnt/Ca+2 signaling in the P301S mouse model of tauopathy

Mutations in the MAPT gene, which encodes the tau protein, are associated with several neurodegenerative diseases, including frontotemporal dementia (FTD), dementia with epilepsy, and other types of dementia. The missense mutation in the Mapt gene in the P301S mouse model of FTD results in impaired...

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Detalles Bibliográficos
Autores principales: Amal, Haitham, Gong, Guanyu, Gjoneska, Elizabeta, Lewis, Sarah M., Wishnok, John S., Tsai, Li-Huei, Tannenbaum, Steven R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6351542/
https://www.ncbi.nlm.nih.gov/pubmed/30696811
http://dx.doi.org/10.1038/s41398-019-0388-7

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