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Caspase-4 disaggregates lipopolysaccharide micelles via LPS-CARD interaction

Lipopolysaccharides (LPS) are a major component of the outer membrane of Gram-negative bacteria and are pathogen-associated molecular patterns recognized by the TLR4/MD2 complex that induces an inflammatory response. Recently, the cytosolic receptors caspase-4/-5/-11 that bind LPS inside the cell an...

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Detalles Bibliográficos
Autores principales: An, Jinsu, Kim, Seong Ho, Hwang, Dohyeon, Lee, Kyung Eun, Kim, Min Jung, Yang, Eun Gyeong, Kim, So Yeon, Chung, Hak Suk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6351570/
https://www.ncbi.nlm.nih.gov/pubmed/30696842
http://dx.doi.org/10.1038/s41598-018-36811-4