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X-ray structure of Fasciola hepatica Sigma class glutathione transferase 1 reveals a disulfide bond to support stability in gastro-intestinal environment

Sigma class GST (Prostaglandin D synthase), FhGST-S1, is present in the excretory–secretory products (ES) of the liver fluke parasite Fasciola hepatica as cargo of extracellular vesicles (EVs) released by the parasite. FhGST-S1 has a well characterised role in the modulation of the immune response;...

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Detalles Bibliográficos
Autores principales:	Line, Kirsty, Isupov, Michail N., LaCourse, E. James, Cutress, David J., Morphew, Russell M., Brophy, Peter M., Littlechild, Jennifer A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6351632/ https://www.ncbi.nlm.nih.gov/pubmed/30696975 http://dx.doi.org/10.1038/s41598-018-37531-5

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