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Induction of human pluripotent stem cells into kidney tissues by synthetic mRNAs encoding transcription factors

The derivation of kidney tissues from human pluripotent stem cells (hPSCs) and its application for replacement therapy in end-stage renal disease have been widely discussed. Here we report that consecutive transfections of two sets of synthetic mRNAs encoding transcription factors can induce rapid a...

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Detalles Bibliográficos
Autores principales:	Hiratsuka, Ken, Monkawa, Toshiaki, Akiyama, Tomohiko, Nakatake, Yuhki, Oda, Mayumi, Goparaju, Sravan Kumar, Kimura, Hiromi, Chikazawa-Nohtomi, Nana, Sato, Saeko, Ishiguro, Keiichiro, Yamaguchi, Shintaro, Suzuki, Sayuri, Morizane, Ryuji, Ko, Shigeru B. H., Itoh, Hiroshi, Ko, Minoru S. H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6351687/ https://www.ncbi.nlm.nih.gov/pubmed/30696889 http://dx.doi.org/10.1038/s41598-018-37485-8

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