Cargando…

Knockdown of SNHG12 suppresses tumor metastasis and epithelial-mesenchymal transition via the Slug/ZEB2 signaling pathway by targeting miR-218 in NSCLC

Non-small cell lung cancer (NSCLC) is a type of lung cancer which has a high mortality and low survival rate. Previous studies have revealed that long non-coding RNAs participate in tumorigenesis and metastasis in NSCLC. In the present study, the function of small nucleolar RNA host gene 12 (SNHG12)...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Yan, Liang, Shuxin, Yu, Yang, Shi, Yankui, Zheng, Hailiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2019
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6351734/ https://www.ncbi.nlm.nih.gov/pubmed/30719111 http://dx.doi.org/10.3892/ol.2018.9880

Ejemplares similares

Downregulation of miR-218 contributes to epithelial–mesenchymal transition and tumor metastasis in lung cancer by targeting Slug/ZEB2 signaling
por: Shi, Z-M, et al.
Publicado: (2017)

MiR-124 targets Slug to regulate epithelial–mesenchymal transition and metastasis of breast cancer
por: Liang, Yong-Jun, et al.
Publicado: (2013)

ERK inactivation enhances stemness of NSCLC cells via promoting Slug-mediated epithelial-to-mesenchymal transition
por: Cai, Shurui, et al.
Publicado: (2022)

miR-101 suppresses the epithelial-to-mesenchymal transition by targeting ZEB1 and ZEB2 in ovarian carcinoma
por: GUO, FEI, et al.
Publicado: (2014)

Knockdown of BAG3 induces epithelial–mesenchymal transition in thyroid cancer cells through ZEB1 activation
por: Meng, X, et al.
Publicado: (2014)

MiR-218 regulates epithelial–mesenchymal transition and angiogenesis in colorectal cancer via targeting CTGF
por: Lun, Weijian, et al.
Publicado: (2018)

LINC01296/miR-141-3p/ZEB1-ZEB2 axis promotes tumor metastasis via enhancing epithelial-mesenchymal transition process
por: Sun, Zhenqiang, et al.
Publicado: (2021)

SPOCK1 promotes the invasion and metastasis of gastric cancer through Slug‐induced epithelial‐mesenchymal transition
por: Chen, Dehu, et al.
Publicado: (2017)

Induction of epithelial-mesenchymal transition (EMT) by Beclin 1 knockdown via posttranscriptional upregulation of ZEB1 in thyroid cancer cells
por: Li, Si, et al.
Publicado: (2016)

The VIM-AS1/miR-655/ZEB1 axis modulates bladder cancer cell metastasis by regulating epithelial–mesenchymal transition
por: Xiong, Yaoyao, et al.
Publicado: (2021)

miR-144-3p inhibited the growth, metastasis and epithelial-mesenchymal transition of colorectal adenocarcinoma by targeting ZEB1/2
por: Li, Taiyuan, et al.
Publicado: (2021)

MDA-9/Syntenin-Slug transcriptional complex promote epithelial-mesenchymal transition and invasion/metastasis in lung adenocarcinoma
por: Wang, Lu-Kai, et al.
Publicado: (2015)

HOXD9 promotes epithelial–mesenchymal transition and cancer metastasis by ZEB1 regulation in hepatocellular carcinoma
por: Lv, Xiupeng, et al.
Publicado: (2015)

PARK2 negatively regulates the metastasis and epithelial-mesenchymal transition of glioblastoma cells via ZEB1
por: Wang, Haiyang, et al.
Publicado: (2017)

USP5 promotes epithelial-mesenchymal transition by stabilizing SLUG in hepatocellular carcinoma
por: Meng, Jing, et al.
Publicado: (2019)

Overexpression of ZEB2‐AS1 promotes epithelial‐to‐mesenchymal transition and metastasis by stabilizing ZEB2 mRNA in head neck squamous cell carcinoma
por: Diao, Pengfei, et al.
Publicado: (2019)

AP-2β inhibits hepatocellular carcinoma invasion and metastasis through Slug and Snail to suppress epithelial-mesenchymal transition
por: Yang, Liu, et al.
Publicado: (2018)

p53 regulates epithelial–mesenchymal transition through microRNAs targeting ZEB1 and ZEB2
por: Kim, Taewan, et al.
Publicado: (2011)

The role of epithelial–mesenchymal transition drivers ZEB1 and ZEB2 in mediating docetaxel‐resistant prostate cancer
por: Hanrahan, Karen, et al.
Publicado: (2017)

FOXO1 inhibits the invasion and metastasis of hepatocellular carcinoma by reversing ZEB2-induced epithelial-mesenchymal transition
por: Dong, Tianxiu, et al.
Publicado: (2016)

miR-186 regulates epithelial–mesenchymal transformation to promote nasopharyngeal carcinoma metastasis by targeting ZEB1()
por: Tang, Liangke, et al.
Publicado: (2023)

Slug Is A Surrogate Marker of Epithelial to Mesenchymal Transition (EMT) in Head and Neck Cancer
por: Steinbichler, T. B., et al.
Publicado: (2020)

Targeting the SPOCK1-snail/slug axis-mediated epithelial-to-mesenchymal transition by apigenin contributes to repression of prostate cancer metastasis
por: Chien, Ming-Hsien, et al.
Publicado: (2019)

LncRNA SNHG6 Induces Epithelial–Mesenchymal Transition of Pituitary Adenoma Via Suppressing MiR-944
por: Mao, Dandan, et al.
Publicado: (2022)

HIF-1α Promotes Epithelial-Mesenchymal Transition and Metastasis through Direct Regulation of ZEB1 in Colorectal Cancer
por: Zhang, Wenjing, et al.
Publicado: (2015)

CPEB4 promotes growth and metastasis of gastric cancer cells via ZEB1-mediated epithelial– mesenchymal transition
por: Cao, Gan, et al.
Publicado: (2018)

Mesenchymal stem cell-derived exosomes enriched with miR-218 reduce the epithelial–mesenchymal transition and angiogenesis in triple-negative breast cancer cells
por: Shojaei, Samaneh, et al.
Publicado: (2023)

Long non‐coding RNA ZEB2‐AS1 promotes the proliferation, metastasis and epithelial mesenchymal transition in triple‐negative breast cancer by epigenetically activating ZEB2
por: Zhang, Guoxin, et al.
Publicado: (2019)

Knockdown of NSD2 Suppresses Renal Cell Carcinoma Metastasis by Inhibiting Epithelial-Mesenchymal Transition
por: Han, Xu, et al.
Publicado: (2019)

GNAQ knockdown promotes bone metastasis through epithelial-mesenchymal transition in lung cancer cells
por: Choi, Ji-Yoon, et al.
Publicado: (2021)

An autocrine TGF-β/ZEB/miR-200 signaling network regulates establishment and maintenance of epithelial-mesenchymal transition
por: Gregory, Philip A., et al.
Publicado: (2011)

miR-1271 inhibits growth, invasion and epithelial–mesenchymal transition by targeting ZEB1 in ovarian cancer cells
por: Jiao, Yanni, et al.
Publicado: (2019)

MiR-218-5p targets LHFPL3 to regulate proliferation, migration, and epithelial–mesenchymal transitions of human glioma cells
por: Li, Zhixiao, et al.
Publicado: (2019)

Effects of miR-340 overexpression and knockdown on the proliferation and metastasis of NSCLC cell lines
por: Zhu, Xidan, et al.
Publicado: (2019)

Elf5 inhibits epithelial mesenchymal transition in mammary gland development and breast cancer metastasis by transcriptionally repressing Snail2/Slug
por: Chakrabarti, Rumela, et al.
Publicado: (2012)

A‐kinase‐interacting protein 1 facilitates growth and metastasis of gastric cancer cells via Slug‐induced epithelial‐mesenchymal transition
por: Chen, Dehu, et al.
Publicado: (2019)

The circRNA circPTPRA suppresses epithelial-mesenchymal transitioning and metastasis of NSCLC cells by sponging miR-96-5p
por: Wei, Siliang, et al.
Publicado: (2019)

MiR-630 Inhibits Endothelial-Mesenchymal Transition by Targeting Slug in Traumatic Heterotopic Ossification
por: Sun, Yangbai, et al.
Publicado: (2016)

MiR-22 suppresses epithelial–mesenchymal transition in bladder cancer by inhibiting Snail and MAPK1/Slug/vimentin feedback loop
por: Xu, Mingjie, et al.
Publicado: (2018)

Sodium new houttuyfonate suppresses metastasis in NSCLC cells through the Linc00668/miR-147a/slug axis
por: Jiang, Rilei, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_635sb8j918s3vef3sf7f2j8vn6