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Upregulated Interleukin 21 Receptor Enhances Proliferation and Epithelial-Mesenchymal Transition Process in Benign Prostatic Hyperplasia

Background: Interleukins (ILs) and related chronic inflammation have been found to contribute to the development of benign prostatic hyperplasia (BPH) in recent decades. As a late member of the ILs family, IL-21 receptor (IL-21R) can modulate cell proliferation, however, IL-21R activity in the prost...

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Detalles Bibliográficos
Autores principales: Xu, Deqiang, Chen, Ping, Xiao, He, Wang, Xinghuan, DiSanto, Michael E., Zhang, Xinhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6351785/
https://www.ncbi.nlm.nih.gov/pubmed/30728806
http://dx.doi.org/10.3389/fendo.2019.00004