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Telomere length and telomerase activity in T cells are biomarkers of high‐performing centenarians

It is generally recognized that the function of the immune system declines with increased age and one of the major immune changes is impaired T‐cell responses upon antigen presentation/stimulation. Some “high‐performing” centenarians (100+ years old) are remarkably successful in escaping, or largely...

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Detalles Bibliográficos
Autores principales: Tedone, Enzo, Huang, Ejun, O’Hara, Ryan, Batten, Kimberly, Ludlow, Andrew T., Lai, Tsung‐Po, Arosio, Beatrice, Mari, Daniela, Wright, Woodring E., Shay, Jerry W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6351827/
https://www.ncbi.nlm.nih.gov/pubmed/30488553
http://dx.doi.org/10.1111/acel.12859