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Telomere length and telomerase activity in T cells are biomarkers of high‐performing centenarians
It is generally recognized that the function of the immune system declines with increased age and one of the major immune changes is impaired T‐cell responses upon antigen presentation/stimulation. Some “high‐performing” centenarians (100+ years old) are remarkably successful in escaping, or largely...
Autores principales: | Tedone, Enzo, Huang, Ejun, O’Hara, Ryan, Batten, Kimberly, Ludlow, Andrew T., Lai, Tsung‐Po, Arosio, Beatrice, Mari, Daniela, Wright, Woodring E., Shay, Jerry W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6351827/ https://www.ncbi.nlm.nih.gov/pubmed/30488553 http://dx.doi.org/10.1111/acel.12859 |
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