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A nuclear lamina‐chromatin‐Ran GTPase axis modulates nuclear import and DNA damage signaling
The Ran GTPase regulates nuclear import and export by controlling the assembly state of transport complexes. This involves the direct action of RanGTP, which is generated in the nucleus by the chromatin‐associated nucleotide exchange factor, RCC1. Ran interactions with RCC1 contribute to formation o...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6351833/ https://www.ncbi.nlm.nih.gov/pubmed/30565836 http://dx.doi.org/10.1111/acel.12851 |