A nuclear lamina‐chromatin‐Ran GTPase axis modulates nuclear import and DNA damage signaling

The Ran GTPase regulates nuclear import and export by controlling the assembly state of transport complexes. This involves the direct action of RanGTP, which is generated in the nucleus by the chromatin‐associated nucleotide exchange factor, RCC1. Ran interactions with RCC1 contribute to formation o...

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Detalles Bibliográficos
Autores principales: Dworak, Natalia, Makosa, Dawid, Chatterjee, Mandovi, Jividen, Kasey, Yang, Chun‐Song, Snow, Chelsi, Simke, William C., Johnson, Isaac G., Kelley, Joshua B., Paschal, Bryce M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6351833/
https://www.ncbi.nlm.nih.gov/pubmed/30565836
http://dx.doi.org/10.1111/acel.12851

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