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Loss of PTEN induces lung fibrosis via alveolar epithelial cell senescence depending on NF‐κB activation

Idiopathic pulmonary fibrosis (IPF) is an aging‐associated disease with poor prognosis. Currently, there are no effective drugs for preventing the disease process. The mechanisms underlying the role of alveolar epithelial cell (AEC) senescence in the pathogenesis of IPF remain poorly understood. We...

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Detalles Bibliográficos
Autores principales: Tian, Yaqiong, Li, Hui, Qiu, Ting, Dai, Jinghong, Zhang, Yingwei, Chen, Jingyu, Cai, Hourong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6351835/
https://www.ncbi.nlm.nih.gov/pubmed/30548445
http://dx.doi.org/10.1111/acel.12858