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Temporal and regional progression of Alzheimer’s disease‐like pathology in 3xTg‐AD mice

Accumulation of amyloid‐β (Aβ) and fibrillary tangles, as well as neuroinflammation and memory loss, are hallmarks of Alzheimer’s disease (AD). After almost 15 years from their generation, 3xTg‐AD mice are still one of the most used transgenic models of AD. Converging evidence indicates that the phe...

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Detalles Bibliográficos
Autores principales: Belfiore, Ramona, Rodin, Alexis, Ferreira, Eric, Velazquez, Ramon, Branca, Caterina, Caccamo, Antonella, Oddo, Salvatore
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6351836/
https://www.ncbi.nlm.nih.gov/pubmed/30488653
http://dx.doi.org/10.1111/acel.12873

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