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Aging differentially modulates the Wnt pro‐survival signalling pathways in vascular smooth muscle cells

We previously reported pro‐survival effects of Wnt3a and Wnt5a proteins in vascular smooth muscle cells (VSMCs). Wnt5a achieved this through induction of Wnt1‐inducible signalling pathway protein‐1 (WISP‐1) consequent to β‐catenin/CREB‐dependent, TCF‐independent, signalling. However, we found that a...

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Detalles Bibliográficos
Autores principales: Brown, Bethan A., Connolly, Georgia M., Mill, Carina E. J., Williams, Helen, Angelini, Gianni D., Johnson, Jason L., George, Sarah J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6351844/
https://www.ncbi.nlm.nih.gov/pubmed/30548452
http://dx.doi.org/10.1111/acel.12844

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