Cargando…
Harnessing cellular aging in human stem cell models of amyotrophic lateral sclerosis
Amyotrophic lateral sclerosis (ALS) is a relentlessly progressive neurodegenerative condition that is invariably fatal, usually within 3 to 5 years of diagnosis. The etiology of ALS remains unresolved and no effective treatments exist. There is therefore a desperate and unmet need for discovery of d...
Autores principales: | Ziff, Oliver J., Patani, Rickie |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6351881/ https://www.ncbi.nlm.nih.gov/pubmed/30565851 http://dx.doi.org/10.1111/acel.12862 |
Ejemplares similares
-
Decoding the relationship between ageing and amyotrophic lateral sclerosis: a cellular perspective
por: Pandya, Virenkumar A, et al.
Publicado: (2020) -
The microglial component of amyotrophic lateral sclerosis
por: Clarke, Benjamin E, et al.
Publicado: (2020) -
Aberrant cytoplasmic intron retention is a blueprint for RNA binding protein mislocalization in VCP-related amyotrophic lateral sclerosis
por: Tyzack, Giulia E, et al.
Publicado: (2021) -
Astrocytes display cell autonomous and diverse early reactive states in familial amyotrophic lateral sclerosis
por: Taha, Doaa M, et al.
Publicado: (2022) -
Experimental and Therapeutic Opportunities for Stem Cells in Multiple Sclerosis
por: Patani, Rickie, et al.
Publicado: (2012)