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Metformin inhibits mitochondrial adaptations to aerobic exercise training in older adults
Metformin and exercise independently improve insulin sensitivity and decrease the risk of diabetes. Metformin was also recently proposed as a potential therapy to slow aging. However, recent evidence indicates that adding metformin to exercise antagonizes the exercise‐induced improvement in insulin...
Autores principales: | Konopka, Adam R., Laurin, Jaime L., Schoenberg, Hayden M., Reid, Justin J., Castor, William M., Wolff, Christopher A., Musci, Robert V., Safairad, Oscar D., Linden, Melissa A., Biela, Laurie M., Bailey, Susan M., Hamilton, Karyn L., Miller, Benjamin F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6351883/ https://www.ncbi.nlm.nih.gov/pubmed/30548390 http://dx.doi.org/10.1111/acel.12880 |
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