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Campylobacter jejuni promotes colorectal tumorigenesis through the action of cytolethal distending toxin

OBJECTIVE: Campylobacter jejuni produces a genotoxin, cytolethal distending toxin (CDT), which has DNAse activity and causes DNA double-strand breaks. Although C. jejuni infection has been shown to promote intestinal inflammation, the impact of this bacterium on carcinogenesis has never been examine...

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Detalles Bibliográficos
Autores principales:	He, Zhen, Gharaibeh, Raad Z, Newsome, Rachel C, Pope, Jllian L, Dougherty, Michael W, Tomkovich, Sarah, Pons, Benoit, Mirey, Gladys, Vignard, Julien, Hendrixson, David R, Jobin, Christian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2019
Materias:	Colon
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6352414/ https://www.ncbi.nlm.nih.gov/pubmed/30377189 http://dx.doi.org/10.1136/gutjnl-2018-317200

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